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Acetyl-L-carnitine
500 mg, 100 capsules
Item Catalog Number: 00449 |
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A major cause of aging is deterioration of the energy-producing components of the cell, resulting in reduced cellular metabolic activity, the accumulation of cellular debris and eventually cell death.1-7 L-carnitine helps maintain cellular energy metabolism by assisting in the transport of fat through the cell membrane and into the mitochondria within the cell, where fats are oxidized to produce the cellular energy ATP.8-13
Acetyl-L-carnitine is the acetylated ester of the amino acid L-carnitine. Acetyl-L-carnitine is an endogenous mitochondrial membrane compound that helps maintain mitochondrial bioenergetics and lowers the increased oxidative stress associated with aging.14 Acetyl-L-carnitine and L-carnitine are absorbed into the bloodstream efficiently. Both are effective at carrying fatty acids across the membrane into the cell where they are burned as energy and utilized efficiently by the mitochondria.15-17 Acetyl-L-carnitine also guards against oxidative damage.18,19 Amyloid-beta peptide is a principal component of senile plaques and is thought to be central to the pathogenesis of the degenerating process. Acetyl-L-carnitine exerts protective effects against A-beta neurotoxicity and oxidative stress.14
L-arginine is a semi-essential amino acid involved in numerous areas of human biochemistry, including ammonia detoxification, hormone secretion, and immune modulation. Arginine is also well known as a precursor to nitric oxide (NO), a key component of endothelial-derived relaxing factor, an endogenous messenger molecule involved in a variety of endothelium-dependent physiological effects in the cardiovascular system.
L-ornithine is a metabolite of arginine in the body, formed as a byproduct of the action of the arginase enzyme on arginine. L-arginine is required for the body to synthesize nitric oxide, which enables the arterial system to retain its youthful elasticity. Nitric oxide also helps to produce endothelial relaxation factor, which is needed by the arterial system to expand and contract with each heartbeat.54-68 L-arginine may also help stimulate the immune system.69-72
Surgical or traumatic injury greatly increases the body’s need for L-arginine, a key building block to maintaining healthy tissue and bone. L-ornithine may also be used for this purpose.73-84
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| References |
| Supplement Facts |
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Serving Size 2 capsule |
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Servings Per Container 50 |
| Amount Per Serving |
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Acetyl-L-Carnitine (from acetyl-L-carnitine hydrochloride) |
1000 mg |
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Other ingredients: rice flour, gelatin, microcrystalline cellulose, vegetable stearate, silica.
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Contains rice.
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, or corn. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives. | | |
| Dosage and Use |
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Take two capsules once or twice daily, or as recommended by a healthcare practitioner. |
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This product is best utilized when taken on an empty stomach with water or juice in divided doses 45 minutes before breakfast and lunch. | |
| Caution |
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For some people, L-carnitine, especially acetyl-Lcarnitine, may have a stimulating effect. Therefore, it may be unwise to take it in the evening. | | Warnings |
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| Related Keywords |
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Amino Acid, Cellular Energy, ATP |
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